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Hydroquinone vs. Alpha Arbutin: Benefits, Key Differences & Effectiveness


  • Hydroquinone works by killing the cells that produce pigmentation and melanin.
  • Products that contain 2% or lower of hydroquinone are sold in U.S
  • Some evidence suggest that hydroquinone can be irritating on skin and may also act as carcinogen.

Alpha Arbutin

  • Alpha Arbutin inhibits the enzymes that stimulate pigment-producing cells.
  • It is safe to use Alpha Arbutin with only 2% concentration or lower.
  • Alpha Arbutin is less irritating and is considered much safer than hydroquinone.

Is Alpha Arbutin the best alternative to Hydroquinone?

Alpha-Arbutin has been proven to have superior results, even when compared to its chemically similar molecules, hydroquinone, and beta-arbutin. In addition to higher efficacy, it also boasts a better safety profile compared to hydroquinone and is more stable when compared to beta-arbutin.

Which is more effective – Alpha Arbutin vs Hydroquinone

Arbutin is a Glycoside, a more natural Hydroquinone derivative. Hydroquinone is one of the most effective skin lightening substances, but because of its potency, it can cause lasting skin damage if not taken under medical care. Alpha Arbutin is a safe and effective alternative to Hydroquinone, with none of the negative side effects.

Hydroquinone has long been the ingredient of choice for more severe hyperpigmentation and melasma due to its intensity, however the hydroquinone commonly used in skin care products is synthetic, aggressive, and can cause serious skin damage if used wrongly. Arbutin is a safer, more natural version of hydroquinone that has been demonstrated to treat melasma and severe dark spots when applied topically. 

Risks of alpha arbutin & hydroquinone & how to use them safely

None of the elements in skincare interact negatively with arbutin. It’s also appropriate for individuals of all skin tones. Even so, it’s possible that it will have a detrimental effect on your skin in a few unusual circumstances. Arbutin is a hydroquinone derivative that is naturally occurring. It can be hydrolyzed to produce hydroquinone under alkaline circumstances.

Redness, irritation, and occasional burning sensations are common symptoms of extremely sensitive skin. Such situations are, however, uncommon. Some people might benefit from a specific strength and composition. However, it is possible that it will be harmful to your health. Always begin with a lower concentration to be on the safe side. Examine the ingredient list as well.

Why to use ALPHA ARBUTIN with NIACINAMIDE for hyperpigmentation?

  • Both inhibits melanin that helps treat pigmentation on skin.
  • Both are gentle and work on hyperpigmentation, dullness and dark spots.
  • Niacinamide prevents transfer of melanin that reduces the occurrence of pigmentation.
  • Alpha Arbutin suppresses tyrosine thus slowing down the process of hyperpigmentation.

Deconstruct’s range of products containing hydroquinone & alpha arbutin 

Brightening Serum 

Niacinamide (10%) and Alpha Arbutin (0.33%) make up this product.

Niacinamide and Alpha Arbutin work together to improve skin texture, balance out skin tone, and fight hyperpigmentation, tanning, and freckles. 0.3 percent Alpha Arbutin lowers melanin synthesis and protects the skin from UV radiation, minimizing tan and whitening the skin when mixed with other ingredients.

Clearing Serum

Alpha Arbutin is 2% and Niacinamide is 5% in this supplement. The distinctive combination of Niacinamide and Alpha Arbutin works by decreasing melanin production, which helps to reduce blemishes, scars, and hyperpigmentation. The 2% Alpha Arbutin in combination acts on tan and brightens the skin by lowering melanin synthesis while also protecting the skin from UV radiation.


Are alpha arbutin and hydroquinone same?

Alpha arbutin, which is frequently referred to as natural hydroquinone, is a more palatable alternative to hydroquinone. Because of its molecular structure, alpha arbutin has a comparable effect to hydroquinone, but with less irritability and melano cytotoxicity.

Is alpha arbutin safer than hydroquinone?

Alpha Arbutin is less irritating than hydroquinone and is thought to be significantly safer.

Can l use alpha arbutin instead of hydroquinone?

Even when compared to structurally identical substances such as hydroquinone and beta-arbutin, alpha-arbutin has been shown to have superior outcomes. It has a better safety profile than hydroquinone, in addition to having a higher effectiveness.

Is alpha arbutin as effective as hydroquinone?

Hydroquinone is one of the most effective skin lightening substances; yet, due to its potency, it can cause lasting skin damage if not taken under medical supervision. It has a better safety profile than hydroquinone, in addition to having a higher effectiveness.

Can I use alpha arbutin and hydroquinone together?

It’s preferable to combine arbutin with other substances that have comparable brightening properties, like vitamin C and AHA, but as with any new product, proceed with caution.

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